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Acidic Amino Acids Impart Enhanced Ca(2+) Permeability and Flux in Two Members of the ATP-gated P2X Receptor Family

P2X receptors are ATP-gated cation channels expressed in nerve, muscle, bone, glands, and the immune system. The seven family members display variable Ca(2+) permeabilities that are amongst the highest of all ligand-gated channels (Egan and Khakh, 2004). We previously reported that polar residues re...

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Detalles Bibliográficos
Autores principales: Samways, Damien S.K., Egan, Terrance M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151611/
https://www.ncbi.nlm.nih.gov/pubmed/17325195
http://dx.doi.org/10.1085/jgp.200609677