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A Role for the S0 Transmembrane Segment in Voltage-dependent Gating of BK Channels

BK (Maxi-K) channel activity is allosterically regulated by a Ca(2+) sensor, formed primarily by the channel's large cytoplasmic carboxyl tail segment, and a voltage sensor, formed by its transmembrane helices. As with other voltage-gated K channels, voltage sensing in the BK channel is accompl...

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Detalles Bibliográficos
Autores principales: Koval, Olga M., Fan, Yun, Rothberg, Brad S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151615/
https://www.ncbi.nlm.nih.gov/pubmed/17296928
http://dx.doi.org/10.1085/jgp.200609662