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A Role for the S0 Transmembrane Segment in Voltage-dependent Gating of BK Channels
BK (Maxi-K) channel activity is allosterically regulated by a Ca(2+) sensor, formed primarily by the channel's large cytoplasmic carboxyl tail segment, and a voltage sensor, formed by its transmembrane helices. As with other voltage-gated K channels, voltage sensing in the BK channel is accompl...
Autores principales: | Koval, Olga M., Fan, Yun, Rothberg, Brad S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151615/ https://www.ncbi.nlm.nih.gov/pubmed/17296928 http://dx.doi.org/10.1085/jgp.200609662 |
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