A Conformation Change in the Extracellular Domain that Accompanies Desensitization of Acid-sensing Ion Channel (ASIC) 3

Acid-sensing ion channels (ASICs) are thought to trigger some forms of acid-induced pain and taste, and to contribute to stroke-induced neural damage. After activation by low extracellular pH, different ASICs undergo desensitization on time scales from 0.1 to 10 s. Consistent with a substantial conf...

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Detalles Bibliográficos
Autores principales: Cushman, Kenneth A., Marsh-Haffner, Josephine, Adelman, John P., McCleskey, Edwin W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151616/
https://www.ncbi.nlm.nih.gov/pubmed/17389250
http://dx.doi.org/10.1085/jgp.200709757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151616/
https://www.ncbi.nlm.nih.gov/pubmed/17389250
http://dx.doi.org/10.1085/jgp.200709757

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