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Uncoupling and Turnover in a Cl(−)/H(+) Exchange Transporter
The CLC-family protein CLC-ec1, a bacterial homologue of known structure, stoichiometrically exchanges two Cl(−) for one H(+) via an unknown membrane transport mechanism. This study examines mutations at a conserved tyrosine residue, Y445, that directly coordinates a Cl(−) ion located near the cente...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151619/ https://www.ncbi.nlm.nih.gov/pubmed/17389248 http://dx.doi.org/10.1085/jgp.200709756 |