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Uncoupling and Turnover in a Cl(−)/H(+) Exchange Transporter

The CLC-family protein CLC-ec1, a bacterial homologue of known structure, stoichiometrically exchanges two Cl(−) for one H(+) via an unknown membrane transport mechanism. This study examines mutations at a conserved tyrosine residue, Y445, that directly coordinates a Cl(−) ion located near the cente...

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Detalles Bibliográficos
Autores principales:	Walden, Michael, Accardi, Alessio, Wu, Fang, Xu, Chen, Williams, Carole, Miller, Christopher
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151619/ https://www.ncbi.nlm.nih.gov/pubmed/17389248 http://dx.doi.org/10.1085/jgp.200709756

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