Alteration of Epithelial Structure and Function Associated with PtdIns(4,5)P(2) Degradation by a Bacterial Phosphatase

Elucidation of the role of PtdIns(4,5)P(2) in epithelial function has been hampered by the inability to selectively manipulate the cellular content of this phosphoinositide. Here we report that SigD, a phosphatase derived from Salmonella, can effectively hydrolyze PtdIns(4,5)P(2), generating PtdIns(...

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Detalles Bibliográficos
Autores principales: Mason, David, Mallo, Gustavo V., Terebiznik, Mauricio R., Payrastre, Bernard, Finlay, B. Brett, Brumell, John H., Rameh, Lucia, Grinstein, Sergio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151621/
https://www.ncbi.nlm.nih.gov/pubmed/17389247
http://dx.doi.org/10.1085/jgp.200609656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151621/
https://www.ncbi.nlm.nih.gov/pubmed/17389247
http://dx.doi.org/10.1085/jgp.200609656

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