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Intracellular Ca(2+) Oscillations, a Potential Pacemaking Mechanism in Early Embryonic Heart Cells
Early (E9.5–E11.5) embryonic heart cells beat spontaneously, even though the adult pacemaking mechanisms are not yet fully established. Here we show that in isolated murine early embryonic cardiomyocytes periodic oscillations of cytosolic Ca(2+) occur and that these induce contractions. The Ca(2+) o...
Autores principales: | Sasse, Philipp, Zhang, Jianbao, Cleemann, Lars, Morad, Martin, Hescheler, Juergen, Fleischmann, Bernd K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151640/ https://www.ncbi.nlm.nih.gov/pubmed/17664344 http://dx.doi.org/10.1085/jgp.200609575 |
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