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β-Scorpion Toxin Modifies Gating Transitions in All Four Voltage Sensors of the Sodium Channel

Several naturally occurring polypeptide neurotoxins target specific sites on the voltage-gated sodium channels. Of these, the gating modifier toxins alter the behavior of the sodium channels by stabilizing transient intermediate states in the channel gating pathway. Here we have used an integrated a...

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Detalles Bibliográficos
Autores principales: Campos, Fabiana V., Chanda, Baron, Beirão, Paulo S.L., Bezanilla, Francisco
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151646/
https://www.ncbi.nlm.nih.gov/pubmed/17698594
http://dx.doi.org/10.1085/jgp.200609719