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β-Scorpion Toxin Modifies Gating Transitions in All Four Voltage Sensors of the Sodium Channel
Several naturally occurring polypeptide neurotoxins target specific sites on the voltage-gated sodium channels. Of these, the gating modifier toxins alter the behavior of the sodium channels by stabilizing transient intermediate states in the channel gating pathway. Here we have used an integrated a...
Autores principales: | Campos, Fabiana V., Chanda, Baron, Beirão, Paulo S.L., Bezanilla, Francisco |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151646/ https://www.ncbi.nlm.nih.gov/pubmed/17698594 http://dx.doi.org/10.1085/jgp.200609719 |
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