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Acetylcholine Receptor Gating: Movement in the α-Subunit Extracellular Domain
Acetylcholine receptor channel gating is a brownian conformational cascade in which nanometer-sized domains (“Φ blocks”) move in staggering sequence to link an affinity change at the transmitter binding sites with a conductance change in the pore. In the α-subunit, the first Φ-block to move during c...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151656/ https://www.ncbi.nlm.nih.gov/pubmed/18040059 http://dx.doi.org/10.1085/jgp.200709858 |