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Evidence for a Deep Pore Activation Gate in Small Conductance Ca(2+)-activated K(+) Channels

Small conductance calcium-gated potassium (SK) channels share an overall topology with voltage-gated potassium (K(v)) channels, but are distinct in that they are gated solely by calcium (Ca(2+)), not voltage. For K(v) channels there is strong evidence for an activation gate at the intracellular end...

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Detalles Bibliográficos
Autores principales: Bruening-Wright, Andrew, Lee, Wei-Sheng, Adelman, John P., Maylie, James
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151660/
https://www.ncbi.nlm.nih.gov/pubmed/17998394
http://dx.doi.org/10.1085/jgp.200709828