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A Quantitative Description of KcsA Gating I: Macroscopic Currents

The prokaryotic K(+) channel KcsA is activated by intracellular protons and its gating is modulated by transmembrane voltage. Typically, KcsA functions have been studied under steady-state conditions, using macroscopic Rb(+)-flux experiments and single-channel current measurements. These studies hav...

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Detalles Bibliográficos
Autores principales: Chakrapani, Sudha, Cordero-Morales, Julio F, Perozo, Eduardo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151670/
https://www.ncbi.nlm.nih.gov/pubmed/17938230
http://dx.doi.org/10.1085/jgp.200709843