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DNA indels in coding regions reveal selective constraints on protein evolution in the human lineage

BACKGROUND: Insertions and deletions of DNA segments (indels) are together with substitutions the major mutational processes that generate genetic variation. Here we focus on recent DNA insertions and deletions in protein coding regions of the human genome to investigate selective constraints on ind...

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Detalles Bibliográficos
Autores principales: de la Chaux, Nicole, Messer, Philipp W, Arndt, Peter F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151769/
https://www.ncbi.nlm.nih.gov/pubmed/17935613
http://dx.doi.org/10.1186/1471-2148-7-191