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Hyperoxia increases ventilator-induced lung injury via mitogen-activated protein kinases: a prospective, controlled animal experiment

INTRODUCTION: Large-tidal volume (V(T)) mechanical ventilation and hyperoxia used in patients with acute respiratory distress syndrome can damage pulmonary epithelial cells through lung inflammation and apoptotic cell death. Hyperoxia has been shown to increase ventilator-induced lung injury, but th...

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Detalles Bibliográficos
Autores principales: Li, Li-Fu, Liao, Shuen-Kuei, Ko, Yu-Shien, Lee, Cheng-Huei, Quinn, Deborah A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151853/
https://www.ncbi.nlm.nih.gov/pubmed/17316425
http://dx.doi.org/10.1186/cc5704