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Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma

BACKGROUND: LIM and SH3 protein 1 (LASP-1), initially identified from human breast cancer, is a specific focal adhesion protein involved in cell proliferation and migration, which was reported to be overexpressed in 8–12 % of human breast cancers and thought to be exclusively located in cytoplasm. M...

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Detalles Bibliográficos
Autores principales: Grunewald, Thomas GP, Kammerer, Ulrike, Kapp, Michaela, Eck, Matthias, Dietl, Johannes, Butt, Elke, Honig, Arnd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151952/
https://www.ncbi.nlm.nih.gov/pubmed/17956604
http://dx.doi.org/10.1186/1471-2407-7-198