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Determination of Epithelial Na(+) Channel Subunit Stoichiometry from Single-Channel Conductances
The epithelial Na(+) channel (ENaC) is a multimeric membrane protein consisting of three subunits, α, β, and γ. The total number of subunits per functional channel complex has been described variously to follow either a tetrameric arrangement of 2α:1β:1γ or a higher-ordered stoichiometry of 3α:3β:3γ...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154365/ https://www.ncbi.nlm.nih.gov/pubmed/17562820 http://dx.doi.org/10.1085/jgp.200609716 |