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Determination of Epithelial Na(+) Channel Subunit Stoichiometry from Single-Channel Conductances

The epithelial Na(+) channel (ENaC) is a multimeric membrane protein consisting of three subunits, α, β, and γ. The total number of subunits per functional channel complex has been described variously to follow either a tetrameric arrangement of 2α:1β:1γ or a higher-ordered stoichiometry of 3α:3β:3γ...

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Detalles Bibliográficos
Autores principales: Anantharam, Arun, Palmer, Lawrence G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154365/
https://www.ncbi.nlm.nih.gov/pubmed/17562820
http://dx.doi.org/10.1085/jgp.200609716