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Age Decline in the Activity of the Ca(2+)-sensitive K(+) Channel of Human Red Blood Cells

The Ca(2+)-sensitive K(+) channel of human red blood cells (RBCs) (Gardos channel, hIK1, hSK4) was implicated in the progressive densification of RBCs during normal senescence and in the mechanism of sickle cell dehydration. Saturating RBC Ca(2+) loads were shown before to induce rapid and homogeneo...

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Detalles Bibliográficos
Autores principales: Tiffert, Teresa, Daw, Nuala, Etzion, Zipora, Bookchin, Robert M., Lew, Virgilio L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154374/
https://www.ncbi.nlm.nih.gov/pubmed/17470662
http://dx.doi.org/10.1085/jgp.200709766