Dual Palmitoylation of Psd-95 Mediates Its Vesiculotubular Sorting, Postsynaptic Targeting, and Ion Channel Clustering

Postsynaptic density-95 (PSD-95/SAP-90) is a palmitoylated peripheral membrane protein that scaffolds ion channels at excitatory synapses. To elucidate mechanisms for postsynaptic ion channel clustering, we analyzed the cellular trafficking of PSD-95. We find that PSD-95 transiently associates with...

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Detalles Bibliográficos
Autores principales: El-Husseini, Alaa E., Craven, Sarah E., Chetkovich, Dane M., Firestein, Bonnie L., Schnell, Eric, Aoki, Chiye, Bredt, David S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156213/
https://www.ncbi.nlm.nih.gov/pubmed/10629226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156213/
https://www.ncbi.nlm.nih.gov/pubmed/10629226

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