Effect of hypoxia and Beraprost sodium on human pulmonary arterial smooth muscle cell proliferation: the role of p27(kip1)

BACKGROUND: Hypoxia induces the proliferation of pulmonary arterial smooth muscle cell (PASMC) in vivo and in vitro, and prostacyclin analogues are thought to inhibit the growth of PASMC. Previous studies suggest that p27(kip1), a kind of cyclin-dependent kinase inhibitor, play an important role in...

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Detalles Bibliográficos
Autores principales: Kadowaki, Maiko, Mizuno, Shiro, Demura, Yoshiki, Ameshima, Shingo, Miyamori, Isamu, Ishizaki, Takeshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2164950/
https://www.ncbi.nlm.nih.gov/pubmed/17974037
http://dx.doi.org/10.1186/1465-9921-8-77

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2164950/
https://www.ncbi.nlm.nih.gov/pubmed/17974037
http://dx.doi.org/10.1186/1465-9921-8-77

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