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The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient cells

The human papillomavirus type 16 E5 protein (HPV16 E5) down-regulates surface expression of HLA-I molecules. The molecular mechanisms underlying this effect are so far unknown. Here we show that HPV16 E5 down-regulates HLA-I surface expression in calnexin-containing but not in calnexin-deficient cel...

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Detalles Bibliográficos
Autores principales: Gruener, Myriam, Bravo, Ignacio G, Momburg, Frank, Alonso, Angel, Tomakidi, Pascal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2164959/
https://www.ncbi.nlm.nih.gov/pubmed/17971213
http://dx.doi.org/10.1186/1743-422X-4-116