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UCP-2 and UCP-3 Proteins Are Differentially Regulated in Pancreatic Beta-Cells

BACKGROUND: Increased uncoupling protein-2 (UCP-2) expression has been associated with impaired insulin secretion, whereas UCP-3 protein levels are decreased in the skeleton muscle of type-2 diabetic subjects. In the present studies we hypothesize an opposing effect of glucose on the regulation of U...

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Detalles Bibliográficos
Autores principales: Li, Yunfeng, Maedler, Kathrin, Shu, Luan, Haataja, Leena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2164968/
https://www.ncbi.nlm.nih.gov/pubmed/18167556
http://dx.doi.org/10.1371/journal.pone.0001397