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Overcoming viral escape with vaccines that generate and display antigen diversity in vivo
BACKGROUND: Viral diversity is a key problem for the design of effective and universal vaccines. Virtually, a vaccine candidate including most of the diversity for a given epitope would force the virus to create escape mutants above the viability threshold or with a high fitness cost. PRESENTATION O...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169210/ https://www.ncbi.nlm.nih.gov/pubmed/18034902 http://dx.doi.org/10.1186/1743-422X-4-125 |