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Analysis of the Roles of 14-3-3 in the Platelet Glycoprotein Ib-IX–Mediated Activation of Integrin α(IIb)β(3) Using a Reconstituted Mammalian Cell Expression Model
We have reconstituted the platelet glycoprotein (GP) Ib-IX–mediated activation of the integrin α(IIb)β(3) in a recombinant DNA expression model, and show that 14-3-3 is important in GPIb-IX signaling. CHO cells expressing α(IIb)β(3) adhere poorly to vWF. Cells expressing GPIb-IX adhere to vWF in the...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169335/ https://www.ncbi.nlm.nih.gov/pubmed/10579727 |