Gelsolin Deficiency Blocks Podosome Assembly and Produces Increased Bone Mass and Strength

Osteoclasts are unique cells that utilize podosomes instead of focal adhesions for matrix attachment and cytoskeletal remodeling during motility. We have shown that osteopontin (OP) binding to the α(v)β(3) integrin of osteoclast podosomes stimulated cytoskeletal reorganization and bone resorption by...

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Detalles Bibliográficos
Autores principales: Chellaiah, Meenakshi, Kizer, Neil, Silva, Matthew, Alvarez, Ulises, Kwiatkowski, David, Hruska, Keith A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169374/
https://www.ncbi.nlm.nih.gov/pubmed/10684249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169374/
https://www.ncbi.nlm.nih.gov/pubmed/10684249

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