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Gelsolin Deficiency Blocks Podosome Assembly and Produces Increased Bone Mass and Strength
Osteoclasts are unique cells that utilize podosomes instead of focal adhesions for matrix attachment and cytoskeletal remodeling during motility. We have shown that osteopontin (OP) binding to the α(v)β(3) integrin of osteoclast podosomes stimulated cytoskeletal reorganization and bone resorption by...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2000
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169374/ https://www.ncbi.nlm.nih.gov/pubmed/10684249 |