Shedding of Syndecan-1 and -4 Ectodomains Is Regulated by Multiple Signaling Pathways and Mediated by a Timp-3–Sensitive Metalloproteinase

The syndecan family of four transmembrane heparan sulfate proteoglycans binds a variety of soluble and insoluble extracellular effectors. Syndecan extracellular domains (ectodomains) can be shed intact by proteolytic cleavage of their core proteins, yielding soluble proteoglycans that retain the bin...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Marilyn L., Wang, Zihua, Park, Pyong Woo, Murphy, Gillian, Bernfield, Merton
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169376/
https://www.ncbi.nlm.nih.gov/pubmed/10684261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169376/
https://www.ncbi.nlm.nih.gov/pubmed/10684261

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