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Regulation and Localization of the Bloom Syndrome Protein in Response to DNA Damage

Bloom syndrome (BS) is an autosomal recessive disorder characterized by a high incidence of cancer and genomic instability. BLM, the protein defective in BS, is a RecQ-like helicase, presumed to function in DNA replication, recombination, or repair. BLM localizes to promyelocytic leukemia protein (P...

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Detalles Bibliográficos
Autores principales: Bischof, Oliver, Kim, Sahn-Ho, Irving, John, Beresten, Sergey, Ellis, Nathan A., Campisi, Judith
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169463/
https://www.ncbi.nlm.nih.gov/pubmed/11309417