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Regulation and Localization of the Bloom Syndrome Protein in Response to DNA Damage
Bloom syndrome (BS) is an autosomal recessive disorder characterized by a high incidence of cancer and genomic instability. BLM, the protein defective in BS, is a RecQ-like helicase, presumed to function in DNA replication, recombination, or repair. BLM localizes to promyelocytic leukemia protein (P...
Autores principales: | Bischof, Oliver, Kim, Sahn-Ho, Irving, John, Beresten, Sergey, Ellis, Nathan A., Campisi, Judith |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169463/ https://www.ncbi.nlm.nih.gov/pubmed/11309417 |
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