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Distinct Domains of Musk Mediate Its Abilities to Induce and to Associate with Postsynaptic Specializations

Agrin released from motor nerve terminals activates a muscle-specific receptor tyrosine kinase (MuSK) in muscle cells to trigger formation of the skeletal neuromuscular junction. A key step in synaptogenesis is the aggregation of acetylcholine receptors (AChRs) in the postsynaptic membrane, a proces...

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Detalles Bibliográficos
Autores principales: Zhou, Heather, Glass, David J., Yancopoulos, George D., Sanes, Joshua R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169478/
https://www.ncbi.nlm.nih.gov/pubmed/10477765