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Depolarization and Neurotrophins Converge on the Phosphatidylinositol 3-Kinase–Akt Pathway to Synergistically Regulate Neuronal Survival

In this report, we have examined the mechanisms whereby neurotrophins and neural activity coordinately regulate neuronal survival, focussing on sympathetic neurons, which require target-derived NGF and neural activity for survival during development. When sympathetic neurons were maintained in subop...

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Detalles Bibliográficos
Autores principales: Vaillant, A.R., Mazzoni, I., Tudan, C., Boudreau, M., Kaplan, D.R., Miller, F.D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169479/
https://www.ncbi.nlm.nih.gov/pubmed/10477751