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Inhibition of Anthrax Lethal Toxin-Induced Cytolysis of RAW264.7 Cells by Celastrol

BACKGROUND: Bacillus anthracis is the bacterium responsible for causing anthrax. The ability of B. anthracis to cause disease is dependent on a secreted virulence factor, lethal toxin, that promotes survival of the bacteria in the host by impairing the immune response. A well-studied effect of letha...

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Detalles Bibliográficos
Autores principales: Chapelsky, Sarah, Batty, Sarah, Frost, Mia, Mogridge, Jeremy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2170518/
https://www.ncbi.nlm.nih.gov/pubmed/18183301
http://dx.doi.org/10.1371/journal.pone.0001421