Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane

Introduction of activated p21-activated kinase (PAK) is sufficient to release primary endothelial cells from contact inhibition of growth. Confluent cells display deficient activation of PAK and translocation of Rac to the plasma membrane at matrix adhesions. Targeting Rac to the plasma membrane res...

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Detalles Bibliográficos
Autores principales: Okada, Tomoyo, Lopez-Lago, Miguel, Giancotti, Filippo G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171182/
https://www.ncbi.nlm.nih.gov/pubmed/16247032
http://dx.doi.org/10.1083/jcb.200503165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171182/
https://www.ncbi.nlm.nih.gov/pubmed/16247032
http://dx.doi.org/10.1083/jcb.200503165

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