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Domain III from class II fusion proteins functions as a dominant-negative inhibitor of virus membrane fusion
Alphaviruses and flaviviruses infect cells through low pH-dependent membrane fusion reactions mediated by their structurally similar viral fusion proteins. During fusion, these class II viral fusion proteins trimerize and refold to form hairpin-like structures, with the domain III and stem regions f...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171229/ https://www.ncbi.nlm.nih.gov/pubmed/16216925 http://dx.doi.org/10.1083/jcb.200507075 |