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Domain III from class II fusion proteins functions as a dominant-negative inhibitor of virus membrane fusion

Alphaviruses and flaviviruses infect cells through low pH-dependent membrane fusion reactions mediated by their structurally similar viral fusion proteins. During fusion, these class II viral fusion proteins trimerize and refold to form hairpin-like structures, with the domain III and stem regions f...

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Detalles Bibliográficos
Autores principales: Liao, Maofu, Kielian, Margaret
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171229/
https://www.ncbi.nlm.nih.gov/pubmed/16216925
http://dx.doi.org/10.1083/jcb.200507075