Temporally resolved interactions between antigen-stimulated IgE receptors and Lyn kinase on living cells

Upon cross-linking by antigen, the high affinity receptor for immunoglobulin E (IgE), FcɛRI, is phosphorylated by the Src family tyrosine kinase Lyn to initiate mast cell signaling, leading to degranulation. Using fluorescence correlation spectroscopy (FCS), we observe stimulation-dependent associat...

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Detalles Bibliográficos
Autores principales: Larson, Daniel R., Gosse, Julie A., Holowka, David A., Baird, Barbara A., Webb, Watt W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171255/
https://www.ncbi.nlm.nih.gov/pubmed/16275755
http://dx.doi.org/10.1083/jcb.200503110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171255/
https://www.ncbi.nlm.nih.gov/pubmed/16275755
http://dx.doi.org/10.1083/jcb.200503110

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