FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion

The overexpression of members of the ErbB tyrosine kinase receptor family has been associated with cancer progression. We demonstrate that focal adhesion kinase (FAK) is essential for oncogenic transformation and cell invasion that is induced by ErbB-2 and -3 receptor signaling. ErbB-2/3 overexpress...

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Detalles Bibliográficos
Autores principales: Benlimame, Naciba, He, Qiang, Jie, Su, Xiao, Dingzhang, Xu, Ying Jie, Loignon, Martin, Schlaepfer, David D., Alaoui-Jamali, Moulay A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171271/
https://www.ncbi.nlm.nih.gov/pubmed/16275754
http://dx.doi.org/10.1083/jcb.200504124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171271/
https://www.ncbi.nlm.nih.gov/pubmed/16275754
http://dx.doi.org/10.1083/jcb.200504124

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