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Terminating Wnt signals: a novel nuclear export mechanism targets activated β-catenin

Nuclear targeting of β-catenin is an obligatory step in Wnt signal transduction, but the factors that control import and export remain to be clarified. In this issue, Hendriksen et al. (p. 785) show that the RanBP3 export factor antagonizes β-catenin/T cell factor (TCF) transcription by targeting th...

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Detalles Bibliográficos
Autores principales: Thorne, Meghan E., Gottardi, Cara J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171287/
https://www.ncbi.nlm.nih.gov/pubmed/16314432
http://dx.doi.org/10.1083/jcb.200510127