Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11

Mre11–Rad50–Nbs1 (MRN) complex involvement in nonhomologous end joining (NHEJ) is controversial. The MRN complex is required for NHEJ in Saccharomyces cerevisiae but not in Schizosaccharomyces pombe. In vertebrates, Mre11, Rad50, and Nbs1 are essential genes, and studies have been limited to cells c...

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Detalles Bibliográficos
Autores principales: Di Virgilio, Michela, Gautier, Jean
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171289/
https://www.ncbi.nlm.nih.gov/pubmed/16330708
http://dx.doi.org/10.1083/jcb.200506029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171289/
https://www.ncbi.nlm.nih.gov/pubmed/16330708
http://dx.doi.org/10.1083/jcb.200506029

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