Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP

Overexpression studies have identified X-linked inhibitor of apoptosis protein (XIAP) as a potent inhibitor of caspases. However, the exact function of endogenous XIAP in regulating mammalian apoptosis is less clear. Endogenous XIAP strictly regulates cytochrome c–dependent caspase activation in sym...

Descripción completa

Detalles Bibliográficos
Autores principales: Potts, Malia B., Vaughn, Allyson E., McDonough, Holly, Patterson, Cam, Deshmukh, Mohanish
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171313/
https://www.ncbi.nlm.nih.gov/pubmed/16344307
http://dx.doi.org/10.1083/jcb.200504082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171313/
https://www.ncbi.nlm.nih.gov/pubmed/16344307
http://dx.doi.org/10.1083/jcb.200504082

Ejemplares similares