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Regulation of Sar1 NH(2) terminus by GTP binding and hydrolysis promotes membrane deformation to control COPII vesicle fission

The mechanisms by which the coat complex II (COPII) coat mediates membrane deformation and vesicle fission are unknown. Sar1 is a structural component of the membrane-binding inner layer of COPII (Bi, X., R.A. Corpina, and J. Goldberg. 2002. Nature. 419:271–277). Using model liposomes we found that...

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Detalles Bibliográficos
Autores principales: Bielli, Anna, Haney, Charles J., Gabreski, Gavin, Watkins, Simon C., Bannykh, Sergei I., Aridor, Meir
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171319/
https://www.ncbi.nlm.nih.gov/pubmed/16344311
http://dx.doi.org/10.1083/jcb.200509095