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Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts
The homotrimeric DNA replication protein proliferating cell nuclear antigen (PCNA) is regulated by both ubiquitylation and sumoylation. We study the appearance and the impact of these modifications on chromosomal replication in frog egg extracts. Xenopus laevis PCNA is modified on lysine 164 by sumo...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171325/ https://www.ncbi.nlm.nih.gov/pubmed/16344309 http://dx.doi.org/10.1083/jcb.200508100 |