Raf-1 sets the threshold of Fas sensitivity by modulating Rok-α signaling

Ablation of the Raf-1 protein causes fetal liver apoptosis, embryonic lethality, and selective hypersensitivity to Fas-induced cell death. Furthermore, Raf-1–deficient cells show defective migration as a result of the deregulation of the Rho effector kinase Rok-α. In this study, we show that the kin...

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Detalles Bibliográficos
Autores principales: Piazzolla, Daniela, Meissl, Katrin, Kucerova, Lucia, Rubiolo, Cristina, Baccarini, Manuela
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171328/
https://www.ncbi.nlm.nih.gov/pubmed/16365167
http://dx.doi.org/10.1083/jcb.200504137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171328/
https://www.ncbi.nlm.nih.gov/pubmed/16365167
http://dx.doi.org/10.1083/jcb.200504137

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