Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial–mesenchymal transition

The Akt family of kinases are activated by growth factors and regulate pleiotropic cellular activities. In this study, we provide evidence for isoform-specific positive and negative roles for Akt1 and -2 in regulating growth factor–stimulated phenotypes in breast epithelial cells. Insulin-like growt...

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Detalles Bibliográficos
Autores principales: Irie, Hanna Y., Pearline, Rachel V., Grueneberg, Dorre, Hsia, Maximilian, Ravichandran, Preethi, Kothari, Nayantara, Natesan, Sridaran, Brugge, Joan S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171329/
https://www.ncbi.nlm.nih.gov/pubmed/16365168
http://dx.doi.org/10.1083/jcb.200505087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171329/
https://www.ncbi.nlm.nih.gov/pubmed/16365168
http://dx.doi.org/10.1083/jcb.200505087

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