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Plx1 is the 3F3/2 kinase responsible for targeting spindle checkpoint proteins to kinetochores
Dynamic attachment of microtubules to kinetochores during mitosis generates pulling force, or tension, required for the high fidelity of chromosome separation. A lack of tension activates the spindle checkpoint and delays the anaphase onset. A key step in the tension–response pathway involves the ph...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171348/ https://www.ncbi.nlm.nih.gov/pubmed/16129782 http://dx.doi.org/10.1083/jcb.200502163 |