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TGF-β maintains dormancy of prostatic stem cells in the proximal region of ducts

We have previously shown that prostatic stem cells are located in the proximal region of mouse prostatic ducts. Here, we show that this region responds differently to transforming growth factor (TGF)-β than the distal ductal region and that under physiological conditions androgens and TGF-β are cruc...

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Detalles Bibliográficos
Autores principales: Salm, Sarah N., Burger, Patricia E., Coetzee, Sandra, Goto, Ken, Moscatelli, David, Wilson, E. Lynette
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171389/
https://www.ncbi.nlm.nih.gov/pubmed/15983059
http://dx.doi.org/10.1083/jcb.200412015