Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1

53BP1 is a key component of the genome surveillance network activated by DNA double strand breaks (DSBs). Despite its known accumulation at the DSB sites, the spatiotemporal aspects of 53BP1 interaction with DSBs and the role of other DSB regulators in this process remain unclear. Here, we used real...

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Detalles Bibliográficos
Autores principales: Bekker-Jensen, Simon, Lukas, Claudia, Melander, Fredrik, Bartek, Jiri, Lukas, Jiri
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171401/
https://www.ncbi.nlm.nih.gov/pubmed/16009723
http://dx.doi.org/10.1083/jcb.200503043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171401/
https://www.ncbi.nlm.nih.gov/pubmed/16009723
http://dx.doi.org/10.1083/jcb.200503043

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