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JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3

Life and death decisions are made by integrating a variety of apoptotic and survival signals in mammalian cells. Therefore, there is likely to be a common mechanism that integrates multiple signals adjudicating between the alternatives. In this study, we propose that 14-3-3 represents such an integr...

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Detalles Bibliográficos
Autores principales: Sunayama, Jun, Tsuruta, Fuminori, Masuyama, Norihisa, Gotoh, Yukiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171419/
https://www.ncbi.nlm.nih.gov/pubmed/16009721
http://dx.doi.org/10.1083/jcb.200409117