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Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling
The mitotic checkpoint is the major cell cycle control mechanism for maintaining chromosome content in multicellular organisms. Prevention of premature onset of anaphase requires activation at unattached kinetochores of the BubR1 kinase, which acts with other components to generate a diffusible “sto...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171436/ https://www.ncbi.nlm.nih.gov/pubmed/16144904 http://dx.doi.org/10.1083/jcb.200505040 |