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FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma

Rhabdomyosarcoma (RMS), the most common pediatric soft-tissue sarcoma, has two major histological subtypes: embryonal RMS (ERMS), which has a favorable prognosis, and alveolar RMS (ARMS), which has a poor outcome. Although both forms of RMS express muscle cell–specific markers, only ARMS cells expre...

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Detalles Bibliográficos
Autores principales: Bois, Philippe R.J., Izeradjene, Kamel, Houghton, Peter J., Cleveland, John L., Houghton, Janet A., Grosveld, Gerard C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171446/
https://www.ncbi.nlm.nih.gov/pubmed/16157701
http://dx.doi.org/10.1083/jcb.200501040