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A local mechanism mediates NAD-dependent protection of axon degeneration

Axon degeneration occurs frequently in neurodegenerative diseases and peripheral neuropathies. Important insight into the mechanisms of axon degeneration arose from findings that the degeneration of transected axons is delayed in Wallerian degeneration slow (Wlds) mice with the overexpression of a f...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhai, Qiwei, Chen, Ying, Lin, Estelle, Gu, Wei, McBurney, Michael W., He, Zhigang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171458/
https://www.ncbi.nlm.nih.gov/pubmed/16043516
http://dx.doi.org/10.1083/jcb.200504028